Dinesh Dhull
Research Interest:
Neurons are not alone in the nervous system. Glial cells constitute the majority of the cells in human brain and are emerging as major regulators of nervous system development, function, and health. Despite their abundance in the nervous system we know surprisingly little about any aspect of glial biology. How diverse are they at the molecular level during any brain insult? How do they interact with neurons? What is their function in the mature brain? Glia have the impressive ability to sense any neural injury and respond by undergoing “reactive gliosis”, a process whereby glia exhibit dramatic changes in morphology and gene expression patterns, migrate to the injury site, and manage brain responses to trauma. Reactive gliosis has been a major topic of study in the field of glial cell biology for over a decade, but molecular pathways mediating neuron-glia signaling after injury have remained largely undefined.
Education:
M. Pharm (Pharmacology; 2007-2009) from ISF College of Pharmacy, Moga, Punjab.
Thesis Title: Neuroprotective Effect of Cyclooxygenase Inhibitors in Experimental Dementia.
Publications:
Dinesh N. Gandhi, G. M. Panchal, Dinesh K. Dhull (2013) Influence of gestational exposure on the effects of prenatal exposure to methyl mercury on postnatal development in rats. Cent Eur J Public Health. 21(1):30-35
Dhull DK, Jindal A, Dhull RK, Aggarwal S, Bhateja D, Padi SS (2012) Neuroprotective effect of cyclooxygenase inhibitors in ICV-STZ induced sporadic Alzheimer's disease in rats. J Mol Neurosci. 46(1):223-35
Dhull DK, Bhateja D, Dhull RK, Padi SS (2012) Differential role of cyclooxygenase isozymes on neuronal density in hippocampus CA1 region of intracerebroventricular streptozotocin treated rat brain. J Chem Neuroanat. 43(1):48-51
Bhateja DK, Dhull DK, Gill A, Sidhu A, Sharma S, Reddy BV, Padi SS(2012) Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: possible neuroprotective mechanisms. Eur J Pharmacol. 674(1):33-43.
Current Details:
Dinesh K. Dhull (JRF)
Department of Neurophysiology
NIMHANS, Bangalore-560029
[email protected]
Neurons are not alone in the nervous system. Glial cells constitute the majority of the cells in human brain and are emerging as major regulators of nervous system development, function, and health. Despite their abundance in the nervous system we know surprisingly little about any aspect of glial biology. How diverse are they at the molecular level during any brain insult? How do they interact with neurons? What is their function in the mature brain? Glia have the impressive ability to sense any neural injury and respond by undergoing “reactive gliosis”, a process whereby glia exhibit dramatic changes in morphology and gene expression patterns, migrate to the injury site, and manage brain responses to trauma. Reactive gliosis has been a major topic of study in the field of glial cell biology for over a decade, but molecular pathways mediating neuron-glia signaling after injury have remained largely undefined.
Education:
M. Pharm (Pharmacology; 2007-2009) from ISF College of Pharmacy, Moga, Punjab.
Thesis Title: Neuroprotective Effect of Cyclooxygenase Inhibitors in Experimental Dementia.
Publications:
Dinesh N. Gandhi, G. M. Panchal, Dinesh K. Dhull (2013) Influence of gestational exposure on the effects of prenatal exposure to methyl mercury on postnatal development in rats. Cent Eur J Public Health. 21(1):30-35
Dhull DK, Jindal A, Dhull RK, Aggarwal S, Bhateja D, Padi SS (2012) Neuroprotective effect of cyclooxygenase inhibitors in ICV-STZ induced sporadic Alzheimer's disease in rats. J Mol Neurosci. 46(1):223-35
Dhull DK, Bhateja D, Dhull RK, Padi SS (2012) Differential role of cyclooxygenase isozymes on neuronal density in hippocampus CA1 region of intracerebroventricular streptozotocin treated rat brain. J Chem Neuroanat. 43(1):48-51
Bhateja DK, Dhull DK, Gill A, Sidhu A, Sharma S, Reddy BV, Padi SS(2012) Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: possible neuroprotective mechanisms. Eur J Pharmacol. 674(1):33-43.
Current Details:
Dinesh K. Dhull (JRF)
Department of Neurophysiology
NIMHANS, Bangalore-560029
[email protected]